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Collagen-deficient mice show signs of osteoarthritis

Osteoarthritis (OA) and degenerative disc disease (DDD) are common, chronic musculoskeletal disorders. Both diseases cause joint pain, loss of function, and decreased quality of life for the more than...

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Researcher Eyes Collagen to Follow Tumor Metastasis

A Medical Center scientist has been awarded a $2 million Era of Hope Scholar Research Award to study how breast cancer cells use collagen fibers to spread, and to investigate whether the process can be...

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Chicken capsules good for aching joints

Chicken collagen can provide relief from rheumatoid arthritis (RA) symptoms. A randomised, controlled trial, published in BioMed Central's open access journal Arthritis Research & Therapy, has...

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Nanoscale changes in collagen are a tipoff to bone health

Using a technique that provides detailed images of nanoscale structures, researchers at the University of Michigan and Detroit's Henry Ford Hospital have discovered changes in the collagen component of...

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Scientists create super-strong collagen

(PhysOrg.com) -- A team of University of Wisconsin-Madison researchers has created the strongest form of collagen known to science, a stable alternative to human collagen that could one day be used to...

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New gene discovered for recessive form of brittle bone disease

Researchers at the National Institutes of Health and other institutions have discovered the third in a sequence of genes that accounts for previously unexplained forms of osteogenesis imperfecta (OI),...

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Causes found for stiff skin conditions

By studying the genetics of a rare inherited disorder called stiff skin syndrome, researchers at the Johns Hopkins University School of Medicine have learned more about scleroderma, a condition...

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Nanostructure of 5,000-year-old mummy skin reveals insight into mummification...

(PhysOrg.com) -- Using cutting-edge microscopy techniques, researchers have gained insight into how human mummies can be extremely well-preserved for thousands of years. A team of scientists from...

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Exposing collagen's double life

(PhysOrg.com) -- Collagen, a type of connective tissue that makes up about 30 percent of the human body, plays many roles. The structural protein is an important component of muscle, skin, bones and...

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Clinical Trial Examines Gene Therapy for Dialysis Patients

(PhysOrg.com) -- A new gene therapy may help sustain dialysis access in patients, eliminating the need for multiple interventions and surgeries and improving their quality of life.

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Collagen manufactured from transgenic tobacco plants

A scientist at the Hebrew University of Jerusalem's Robert H. Smith Faculty of Agriculture, Food and Environment has succeeded in producing a replica of human collagen from tobacco plants - an...

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Investigational eye treatment: Corneal collagen crosslinking research study

The Cornea and Laser Eye Institute, with Principal Investigator, Peter S. Hersh M.D., is conducting a research study to study the safety and effectiveness of corneal collagen crosslinking (CXL) using...

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The Achilles' heel of tendons

Tendons are the body's marionette strings, connecting bones to muscles that raise an eyebrow or propel us into a full run. That is, until an unusually forceful or awkward pull on the strings leaves us...

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From dolphins to dinosaurs -- how fine detail is preserved in fossils

(PhysOrg.com) -- Why do some fossils preserve soft tissue in very fine detail while others most of the detail is lost? After death there is a race against time between soft tissue destruction and...

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Key to tissue growth may be in anti-wrinkle cream

The first study to investigate the chemical structure of an advanced class of anti-wrinkle cream has shown that it could be used to promote wound healing and regenerative medicine.

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Unlocking the past with the West Runton Elephant

(PhysOrg.com) -- Researchers from the University of York and Manchester have successfully extracted protein from the bones of a 600,000 year old mammoth, paving the way for the identification of...

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Citrate key in bone's nanostructure

Bone is one of nature's surprising "building materials." Pound-for-pound it's stronger than steel, tough yet resilient. Scientists at the U.S. Department of Energy's Ames Laboratory have identified the...

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New evidence backs up claim of dinosaur soft tissue find

(PhysOrg.com) -- In a new study, biochemist James San Antonio and colleagues offer evidence to support the claims by Mary Higby Schweitzer back in 2005, that she and her colleagues had unearthed a soft...

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US approves cell therapy injection for wrinkles

US regulators have approved a new type of therapy that uses a person's own skin cells to create an injectable cosmetic plumper to smooth out laugh lines, Fibrocell Science said Wednesday.

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Synthetic collagen from maize has human properties

Synthetic collagen has a wide range of applications in reconstructive and cosmetic surgery and in the food industry. For proper function in animals a certain number of prolines within the protein need...

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